Some Single-Nucleotide Polymorphisms of the TSSK2 Gene May be Associated With Human Spermatogenesis Impairment
نویسندگان
چکیده
منابع مشابه
Some single-nucleotide polymorphisms of the TSSK2 gene may be associated with human spermatogenesis impairment.
Tssk2, a member of the testis-specific serine/threonine kinase (TSSK) family, is expressed predominantly in the testis and is crucial for the formation and function of sperm cells in the mouse. Targeted deletion of Tssk1 and Tssk2 in male chimeric mice caused infertility because of haploinsufficiency of the genes. Therefore, it is reasonable to postulate that mutations in the human homolog TSSK...
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Background: Tssk2, a member of the testis specific serine/threonine kinase (TSSK) family, is expressed predominantly in the testis and crucial for the formation and function of the sperm cells in mouse. Targeted deletion of Tssk1 and 2 in male chimeric mice caused infertility due to haploinsufficiency of the genes. Therefore it is reasonable to postulate that mutations in its human homologue TS...
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ژورنال
عنوان ژورنال: Journal of Andrology
سال: 2009
ISSN: 0196-3635
DOI: 10.2164/jandrol.109.008466